Host of No Priors: AI, Machine Learning, Tech, & Startups.

Coinbase’s Everything Exchange: Agentic Finance, Stablecoins & Tokenization with CEO Brian Armstrong
Sep 10, 2026 · 45:10
Coinbase CEO Brian Armstrong argues his exchange is becoming the 'Everything Exchange' while preparing to bank AI agents. Armstrong tells Elad Gil that 88% of Coinbase revenue is non-Bitcoin trading, and details tokenized stocks, stablecoin payments settling in under one second for under $0.01, and prediction markets at a $100 million revenue run rate within months. He explains 76% of agentic commerce transactions are under $0.30, below card fee minimums; Coinbase built crypto wallets and the X402 protocol so agents can hold accounts and pay each other. He also describes Coinbase's internal AI 'brain' system for recursive self-improvement and New Limit, his longevity startup, whose epigenetic reprogramming platform begins a phase-one trial in alcoholic liver disease next year.

Redefining Chip Architecture with Arm CEO Rene Haas
Sep 3, 2026 · 37:07
Arm CEO Rene Haas argues that the CPU, not the accelerator, remains the heart of every system: AI workloads still depend on microprocessors to orchestrate tokens, so Arm moved from licensing IP to building full compute subsystems, including the Arm AGI CPU for Meta. He says the shift was driven by customers like Meta who wanted complete solutions rather than components, and that Arm's design wins in smartphones, data centers and automobiles prove the model. Haas contends supply constraints in memory, substrates and advanced packaging will throttle industry growth for three to five years, making US fab capacity a national-security priority. He predicts AI will become a utility embedded in every device, from edge sensors to robots, and that fears of job loss are overstated because electricians, engineers and skilled tradespeople will be needed in greater numbers to build out data centers, fabs and the physical infrastructure AI requires.

Rethinking Legacy Data Infrastructure with Eon Co-Founders Ofir Ehrlich and Gonen Stein
Aug 27, 2026 · 34:51
Eon co-founders Ofir Ehrlich and Gonen Stein join Elad Gil to argue that data, not compute or models, is the enterprise's moat, and their cloud backup now serves as a data foundation for AI. They cite Google's $10 million purchase of Spirit Airlines' data as proof that real-world data is gold, and say Eon maps, classifies, and masks scattered data to feed LLMs without breaking security or compliance. They warn that AI agents with legitimate permissions are creating ransomware-scale threats at extreme velocity, so companies must assume breach from non-human actors. They contrast the slow cloud era with today's faster, fear-driven AI adoption, where forward-deployed engineers and PLG reshape how legacy enterprises buy software. They say agents multiply actors, making dashboards essential.

Building an Autonomous Enterprise for Real-World Services with Netic Founder Melisa Tokmak
Jul 31, 2026 · 34:30
Melisa Tokmak, founder and CEO of Netic, tells Elad Gil how Netic's autonomous AI platform acts as an intermediary for essential services like HVAC, pet care, and roofing, with over 70% of customers now AI-first. She explains why she built a product company rather than an AI roll-up, and how selling to 'slow' industries is easier than assumed—they're value-focused and tech-forward. Big labs aren't threats due to focus and last-mile orchestration; robotics is decades away for these jobs. She screens for agency by asking candidates the hardest thing they've done, and sees private equity now demanding measurable ROI. Her five-year vision is an 'autonomous enterprise' where AI handles everything except physical labor; she is most excited about AI's impact on education and expanding agency.

Travel Through the Lens of AI with with Booking.com CEO Glenn Fogel
Jul 9, 2026 · 41:05
Booking Holdings CEO Glenn Fogel tells Elad Gil how he rode Priceline from the dot-com bust to a 1000x gain, arguing AI is a tool, not a threat, to travel. Fogel, who joined a week before the Nasdaq peaked, recalls the stock falling to $1 before a reverse split, and sees the same boom-bust pattern in AI. He shows how agentic tools like Priceline's Penny handle complex trips and cut customer service costs 10% per contact, while Booking invests $700 million in AI and tech. Yet he says there are no moats: scale like 8.6 million alternative accommodation listings only helps, and constant innovation is the only defense. He defends returning cash to shareholders—40% of shares bought back in a dozen years—and warns that AI job displacement demands upskilling, not rejection of technology.
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